High-risk criteria 


Speak with your doctor if you see on the same side of your family (father or mother’s):

  • Several family members with CRC*, especially if they are 1st and 2nd-degree relatives;
  • One or more relatives with CRC before the age of 50;
  • Several cases of CRC, but also of other cancers** associated with hereditary syndromes of colorectal cancer***;
  • Several relatives diagnosed for a second time with a CCR, which is not a relapse of the first one but a new cancer (de novo CRC –a new origin);
  • Close relatives with a mutation/genetic change associated with a hereditary CCR syndrome

*CRC - colorectal cancer
** Especially endometrial cancer and/or stomach cancer
****A hereditary cancer syndrome is when an inherited mutation predisposes the individual to develop more than one type of cancer. Examples of colorectal syndromes include HNPCC, FAP, attenuated FAP or MAP 

If you see any of these criteria in your family history, talk with your doctor and ask for information on the available genetic services or  Familial Cancer Services .

You can understand better the process of referral by your doctor to these services  aqui .

Clinical criteria that indicate that a genetic study should be done:

  • First-degree relatives of a CRC patient, who is known to carry a mutation linked to the disease
  • Individuals with or without colorectal cancer who fill the  Amsterdam criteria
  • Individuals with colorectal cancer who fill the  Bethesda criteria/guidelines  

Do not forget though:

  • even if you belong to a family with a history of colorectal cancer, this does not mean that you will develop the disease;
  • there are several ways to manage an increased risk and prevent the disease
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Know… side effects leaflets for colorectal cancer treatment. Learn how to cross this period with more tranquility. (see)
Know… the interactive "familial history", allows the construction of a graphic with the history of colorectal cancer in your family. (see)
Know… how hereditary cancers are usually transmitted, and what are the implications of having a genetic change (mutation) in the body (see)
Know… what is a polyp? How to avoid colorectal cancer? What differences distinguish the various types of tumors? (see)
Know… what you know about familial colorectal cancer: complete our 7-question "expert " quiz. (see)
Know… more about sporadic colorectal cancer, and test your knowledge using our 7-question quiz. (see)